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National Toxicology Program Us Department of Health and Human Services

By Shelby, Michael D., Ph. D.

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Book Id: WPLBN0000218700
Format Type: PDF eBook
File Size: 1.5 MB
Reproduction Date: 2005
Full Text

Title: National Toxicology Program Us Department of Health and Human Services  
Author: Shelby, Michael D., Ph. D.
Volume:
Language: English
Subject: Government publications, United Nations., United Nations. Office for Disarmament Affairs
Collections: Government Library Collection, Disarmament Documents
Historic
Publication Date:
Publisher: United Nations- Office for Disarmament Affairs (Unoda)

Description
Government Reference Publication

Excerpt
Excerpt: 1.0 CHEMISTRY, USE, AND HUMAN EXPOSURE 1.1 Chemistry 1.1.1 Nomenclature The Chemical Abstracts Service registry number for genistein is 446-72-0. ChemIDplus (1) synonyms for genistein include 4,5,7-trihydroxyisoflavone, 5,7,4-trihydroxyisoflavone, genisterin, prunetol, and sophoricol. Isoflavones such as genistein can be conjugated to glucose or other carbohydrate moieties. Carbohydrate conjugates are generically called glycosides and glucose conjugates are called glucosides. Genistein glucoside is called genistin. The term ?total genistein? is used in this report to refer to genistein aglycone and its conjugates. In some studies, genistein has been administered to humans or experimental animals to model effects of dietary soy-based foods. CERHR has produced a report specifically on soy formula that will consider effects of dietary soy products. The current report will be restricted to considerations of effects of genistein itself. In some instances, studies using administration of isoflavone mixtures may be considered marginally useful in evaluating possible effects of genistein. The Expert Panel recognizes that use of a mixture of isoflavones may not adequately model the effects of genistein or of dietary soy products.

 

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